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From DukeMedNews.org
A Duke University Medical Center pharmacologist, Mohamed Abou-Donia, Ph.D., is recommending caution when using the insecticide DEET, after his animal studies last year found the chemical causes diffuse brain cell death and behavioral changes in rats after frequent and prolonged use.
His numerous studies in rats, two of them published last year, clearly demonstrate that frequent and prolonged applications of DEET cause neurons to die in regions of the brain that control muscle movement, learning, memory and concentration. Moreover, rats treated with an average human dose of DEET (40 mg/kg body weight) performed far worse than control rats when challenged with physical tasks requiring muscle control, strength and coordination. Such effects are consistent with physical symptoms in humans reported in the medical literature, especially by Persian Gulf War veterans, said Abou-Donia.
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